Sodium Bicarbonate Injection (box of 1 vial)
Sodium Bicarbonate Injection (box of 1 vial)
*Packaging color may differ according to distribution region.

Sodium Bicarbonate Injection

Sodium Bicarbonate Injection is indicated for the treatment of metabolic acidosis. ISO and GMP guidelines are strictly followed by AdvaCare Pharma during the production of pharmaceutical injections, ensuring their safety.



What is Sodium Bicarbonate?

Therapeutic Class:

Active Ingredients: Sodium Bicarbonate

Sodium Bicarbonate Injections are used to treat metabolic acidosis caused by severe renal disease, severe primary lactic acidosis, uncontrolled diabetes, or cardiac arrest. It is also used to treat this condition when caused by circulatory insufficiencies caused by shock or severe dehydration.

This medication is indicated for the treatment of cardiac conduction delays and QRS prolongation.

Sodium Bicarbonate is an alkalinizing agent. It works by increasing plasma bicarbonate, buffering excess hydrogen ion concentration, raising blood pH, and reversing the clinical manifestations of acidosis.

Sodium Bicarbonate Injections are an aqueous, sterile, nonpyrogenic, and hypertonic solution of sodium bicarbonate with no bacteriostat, antimicrobial agent, or added buffer.

AdvaCare Pharma is a trusted global exporter of Sodium Bicarbonate Injections. This medication is produced in our GMP-certified facilities in China, India, and the USA. Our manufacturing facilities are regularly inspected to ensure they comply with WHO's standards, rules, and regulations.

Why are we a leading Sodium Bicarbonate manufacturer?

AdvaCare Pharma is an American-owned pharmaceutical company that specializes in the manufacture of Sodium Bicarbonate Injection and other quality-assured injectable medications for the worldwide market. Over the past twenty years, we’ve built our reputation on reliable, efficacious, and affordable medical products and custom-tailored marketing plans to meet regional demands.


What is Sodium Bicarbonate used for?

It's used to treat metabolic acidosis (too much acid in the blood) that is caused by conditions such as:

  • cardiac arrest
  • circulatory problems due to severe dehydration or shock
  • drug or alcohol toxicities
  • extracorporeal circulation of blood
  • severe primary lactic acidosis
  • severe renal disease
  • uncontrolled diabetes

It's also used to treat cardiac conduction delays and QRS prolongation.

What dose should be given?

For cardiac arrest, the usual dose is 1mEq/kg/dose, given once by IV. After the initial treatment, doses are depended on the arterial blood pH and PaO2.

For hyperkalemia, the usual dose is 50 mEq, given over 5 minutes IV.

For non-threatening metabolic acidosis, the usual dose is 2-6 mEq/kg, given by IV infusion over 4 to 8 hours,

For severe metabolic acidosis (not including hypercarbic acidosis), the usual dose is 90-180 mEq/L, given at a rate of 1-1.5L for the first hour.

The exact dosage is based on medical condition, response to the treatment, age, and weight. Refer to a doctor or healthcare professional for guidelines on dosage.

Side Effects

As with all pharmaceuticals, some unwanted effects can occur from the use of Sodium Bicarbonate Injection.

Common side effects include, but may not be limited to:

  • ulcers
  • skin tissue loss at the injection site

Serious side effects may include:

  • signs of an allergic reaction
  • seizures
  • metabolic alkalosis

For a comprehensive list of all side effects, consult a doctor or pharmacist.

If any symptom persists or gets worse, or you notice any other symptoms, please call your doctor.


Do NOT use Sodium Bicarbonate Injection if:

  • You are allergic to any of the ingredients.
  • You have any breathing or blood abnormalities.
  • You are having difficulty passing urine or are passing more urine than usual.
  • You are dehydrated.
  • You have high blood pressure.
  • You have problems with your liver.
  • You have heart problems.
  • You have eclampsia.

Due to possible drug interactions, consult with your doctor about any medications you are taking before your treatment.

This medication may not be suitable for people with certain conditions, so it is important to consult with a doctor if you have any health conditions.

*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.

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