Sulfadiazine + Trimethoprim Boluses (box of 50 boluses)
Sulfadiazine + Trimethoprim Boluses (box of 50 boluses)
*Packaging color and/or animals may vary according to distribution region.

Sulfadiazine + Trimethoprim Boluses

Sulfadiazine + Trimethoprim Boluses are a combination medicine indicated for bacterial or microbial illnesses in livestock. AdvaCare Pharma is a trusted manufacturer of veterinary boluses. Our veterinary range comprises more than 400 GMP and ISO-certified products distributed across the globe.



What is Sulfadiazine + Trimethoprim?

Therapeutic Class:
Target Species:

Active Ingredients: Sulfadiazine, Trimethoprim

Sulfadiazine + Trimethoprim Boluses are an antibiotic/antimicrobial combination drug used to treat infections in animals like horses, goats, sheep, camels, and cows. This medicine is indicated for the treatment of certain gastrointestinal, respiratory, and urinary tract infections caused by susceptible microorganisms.

These boluses contain the active ingredients Sulfadiazine and Trimethoprim. Sulfadiazine is classified as a sulfonamide antibiotic. It displays action against most gram-positive and many gram-negative bacteria. It works by inhibiting folic acid synthesis within the bacteria. Trimethoprim is classified as an antibiotic and folate synthesis inhibitor.

The combination shows a broad range of activity against gram-positive and gram-negative bacteria like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp.

Sulfadiazine + Trimethoprim Boluses is a GMP-certified product available for exportation by AdvaCare Pharma. This medication is part of our comprehensive catalog of veterinary supplies which are available for distribution. Our manufacturing factories are located in China, India, and the USA.

Why are we a top Sulfadiazine + Trimethoprim Boluses manufacturer?

AdvaCare Pharma is an American-owned and operated company specializing in the manufacture of veterinary medicines. As part of our range of 250+ veterinary formulations, we manufacture Sulfadiazine + Trimethoprim Boluses under strict GMP guidelines, ensuring efficacy. Our veterinary distributors have confidence in the quality of our products, making AdvaCare Pharma a leading supplier in countries where dependable, cost-effective livestock medications are in high demand.


What is Sulfadiazine + Trimethoprim used for?

It's used to treat infections such as:

It is also used for the treatment or prevention of post-parturient infections, including vaginitis and metritis.

What animals can be treated with Sulfadiazine + Trimethoprim Boluses?

It's recommended for horses and livestock animals like camels, cattle, ѕhеер, and gоаtѕ.

How should Sulfadiazine + Trimethoprim Bolus be stored?

They should be stored in a dark, dry location below 25°C. Keep the boluses in the blister packs until usage.

What is the withdrawal period for Sulfadiazine + Trimethoprim?

The withdrawal time is 15 days for meat.


How much Sulfadiazine + Trimethoprim should be given to livestock?

The usual dose is 1 bolus per 40kg of body weight. The treatment should continue until two days after the symptoms have resolved.

This medicine may be administered by hand, balling gun, or a dosing bottle.

Side Effects

As with all pharmaceuticals, some unwanted effects can occur from the use of Sulfadiazine + Trimethoprim Boluses. Serious side effects may include:

  • allergic reaction, including anaphylaxis
  • urine crystals
  • central nervous toxicity
  • liver damage
  • temporary paralysis in horses

For a comprehensive list of all possible side effects of this medication, consult a veterinary physician.


Do NOT use Sulfadiazine + Trimethoprim Bolus for an animal that:

  • has a known allergy or hypersensitivity to any of the ingredients.
  • has liver damage or a blood cell disease.
  • is an animal with a mature rumen.

Treatment with this drug should be administered with caution for an animal that is dehydrated.

There are known interactions between these medications and drugs such as amantadine, antacids, cyclosporine, digoxin, thiazide diuretics, warfarin, methotrexate, phenytoin, tricyclic antidepressants, pyrimethamine, potassium supplements, and potassium-sparing agents.

Wear protective gloves while handling these boluses. This product should not be handled by those sensitive to sulfonamides.

*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.

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