Always consult a medical doctor or patient care specialist before using tetanus antitoxin.
Indications and Usage
Tetanus antitoxin is indicated for booster injection only for individuals 7 years of age or older. For children under 7 years of age, tetanus injections are one of the routine vaccinations which is scheduled at 4-8 weeks, 15-20 months, and 5-6 years of age. Individuals 7 years of age or older are given tetanus and diphtheria toxoids.
Tetanus antitoxinis contraindicated in patients with developed hypersensitivity towards tetanus antitoxin. It is also contraindicated in any patients with anaphylactic reaction, febrile illnesses, or acute infection.
Do not take tetanus antitoxin if:
- You are allergic to tetanus antitoxin or other containing ingredients;
- You have Guillain-Barré syndrome (GBS);
- You have history of systemic allergic or neurologic reactions.
Adequate immunization by routine boosters in non-pregnant women of child-bearing age can obviate the need to vaccinate women during pregnancy. Tetanus antitoxin injection does not affect the safety of mothers who are breastfeeding or their infants.
Administration and Dosage
Refer to your doctor or pharmacist for guidelines on tetanus antitoxin dose. Do not exceed what they advise. The usual tetanus antitoxin dose for an adult weighing up to 29.5kg is 3000 to 5000IU as a single dose intramuscularly. The usual tetanus antitoxin dose for children is 1500IU intramuscularly.
Tetanus antitoxin should not be used in the routine treatment of traumatic wounds. If the wound is extensive with a high risk of tetanus infection, antitoxin (preferably the human immunoglobulin) should be injected intramuscularly at the earliest possible moment after infliction of the injury. If equine antitoxin is used, the dose ranges from 1500 to 6000 units.
This preparation of tetanus antitoxin should not be used if human anti-tetanus immunoglobulin injection is available. It should be used with great caution if the patient is subject to allergic diseases such as asthma or infantile eczema, or exhibited an allergic reaction to any previous antiserum injection.
Tetanus antitoxin injections may interact with medications such as blood thinners, corticosteroids, cancer chemotherapy, drugs that weaken the immune system, or other recent vaccinations.
Consult with your doctor about any medication you are taking before your treatment with tetanus antitoxin.
Symptoms of overdose include trouble breathing and passing out. These symptoms should be reported to a medical professional. If you experience any of these symptoms, seek medical help urgently.
Mild anaphylactic reactions and serum sickness can be observed.
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