Naloxone HCL Injection (box of 10 ampoules)
Naloxone HCL Injection (box of 10 ampoules)
*Packaging color may differ according to distribution region.

Naloxone HCL Injection

Naloxone HCL Injection is administered to treat opioid overdose or reverse opioid depression. The production process of pharmaceutical injections by AdvaCare Pharma undergoes routine inspections to guarantee quality and safety.



What is Naloxone HCL?

Active Ingredients: Naloxone HCL

Naloxone HCL Injection is used to treat a suspected opioid overdose or reverse opioid depression due to opioids, nalbuphine, pentazocine, or dextropropoxyphene. It is also administered to treat newborns with respiratory or CNS depression that is caused by analgesic administration to the mother.

Naloxone is classified as a centrally-acting opioid antagonist. It works by blocking the effects of opiates in the brain.

This medication is produced and exported by AdvaCare Pharma. Naloxone HCL Injection is manufactured in our facilities in China, India, and the USA. Our factories comply with WHO rules and regulations, and we regularly inspect these facilities to ensure they meet these high standards.

Why are we a leading Naloxone manufacturer?

AdvaCare Pharma is an American-owned pharmaceutical company that specializes in the manufacture of Naloxone HCL Injection and other quality-assured injectable medications for the worldwide market. Over the past twenty years, we’ve built our reputation on reliable, efficacious, and affordable medical products and custom-tailored marketing plans to meet regional demands.


What is Naloxone HCL used for?

It is used to block or reverse the effects of opioid medications.

How is Naloxone HCL Injection used?

This medication has been manufactured as a solution, which is intended to be administered by intravenous, intramuscular or subcutaneous injection or by IV infusion.

What dose should be given?

For opioid overdose, the usual dose for adults is 0.4-2mg, given IV/IM or SC. If needed, repeat doses at 2-3 minute intervals. After a total dose of 10mg, if there is no improvement, the diagnosis should be reevaluated.

For opioid overdose in neonates, the usual dose is 0.01mg/kg, given IV/IM/SC. Repeat doses at 2-3 minute intervals, as needed.

For opioid overdose in children, the usual dose is 0.01mg/kg, given IV. The dose may be raised to 0.1mg/kg if needed.

To reverse opioid sedation, the usual initial dose for adults is 0.1-0.2mg, given at 2-3 minute intervals. Smaller doses are typically sufficient for the partial reversal of opioid depression after surgery.

To reverse opioid sedation in neonates, the usual dose is 0.01mg/kg, given IV/IM/SC. Repeat doses at 2-3 minute intervals, as needed.

To reverse opioid sedation in children, the usual dose is 0.005-.01mg/kg, given IV. Repeat doses at 2-3 minute intervals, as needed.

Side Effects

As with all pharmaceuticals, some unwanted effects can occur from the use of Naloxone HCL Injection.

Naloxone may cause sudden opioid withdrawal symptoms, such as:

  • gastrointestinal effects (nausea, vomiting, diarrhea, abdominal pain)
  • sweating, fever, or body aches
  • tremors, shivering, tachycardia
  • runny nose
  • restlessness or irritability

In infants younger than 4 weeks old, withdrawal symptoms may be life-threatening if not treated. Symptoms may include crying, stiffness, or seizures.

For a comprehensive list of all side effects, consult a doctor or pharmacist.

If any symptom persists or gets worse, or any new symptoms appear, please call your doctor.


Do NOT use Naloxone HCL Injection if: • You are allergic or hypersensitive to any of the ingredients.

This medication may not be suitable for people with certain conditions, including:

This medicine should only be used during pregnancy and breastfeeding if the benefits outweigh the risks. Consult a doctor or healthcare professional before treatment.

*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.

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Why AdvaCare Pharma?

As an industry leader, we are aware of our responsibility to provide affordable and sustainable solutions to improve healthcare worldwide.

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