Caffeine Citrate Injection (box of 10 ampoules)
Caffeine Citrate Injection (box of 10 ampoules)
*Packaging color may differ according to distribution region.

Caffeine Injection

Caffeine Citrate Injection is used as a CNS stimulant for premature infants. AdvaCare Pharma, a medical manufacturer and distributor, produces these pharmaceutical injections according to the highest quality standards in its ISO/GMP-certified facilities.



What is Caffeine Citrate?

Therapeutic Class:

Active Ingredients: Caffeine Citrate

Caffeine Citrate Injection is a drug used to treat short-term breathing problems in premature infants who are between 28 and 32 weeks of gestational age. Apnea of prematurity in neonates is caused by an underdeveloped breathing center. This medication is not recommended for long-term treatment.

Caffeine Citrate is classified as a central nervous system stimulant. It works by stimulating the respiratory centers of the body and increases respiratory rate, cardiac output and blood pressure. This action helps improve the supply of oxygen throughout the body and the brain.

AdvaCare Pharma is a producer and exporter of Caffeine Citrate Injection. This medicine is produced in our GMP-certified facilities in China, India, and the USA. These facilities are regularly audited to ensure they comply with our high standards for health, safety, and environmental standards.

Why are we a leading Caffeine Citrate manufacturer?

AdvaCare Pharma is a leading manufacturer of Caffeine Citrate Injection. To ensure the quality of our pharmaceutical products, we adhere to stringent GMP guidelines at our manufacturing facilities. We partner with distributors, hospitals, pharmacies, NGOs, and government institutions across over 45 markets worldwide, and our track record over the past two decades demonstrates that AdvaCare Pharma is a reliable supplier dedicated to high-quality and efficacious products.


What is Caffeine Citrate used for?

It is used to treat short-term apnea of prematurity.

How is Caffeine Citrate Injection used?

This medication has been manufactured as a solution. It is intended to be injected intravenously slowly over 10-30 minutes.

What dose should be given?

The usual dose is 30mg/kg per dose, given by IV. After 24 hours, 5mg/kg per dose can be given. Dosage should be adjusted based on serum levels.

Side Effects

As with all pharmaceuticals, some unwanted effects can occur from the use of Caffeine Citrate Injection.

Common side effects include, but may not be limited to: • feeding intolerance

Seek medical attention if:

  • sleep apnea continues
  • increased heart rate
  • restlessness, jitteriness or shaking
  • increased diaper wetting
  • abdominal distension
  • vomiting
  • bloody stools

For a comprehensive list of all side effects, consult a doctor or pharmacist.

If any symptom persists or gets worse, or any new symptoms appear, please call your doctor.


Do NOT use Caffeine Citrate Injection if: • the infant is allergic or hypersensitive to any of the ingredients.

This medication may not be suitable for patients with certain conditions, including:

Some drugs are known to interact with Caffeine Citrate, such as riociguat, viloxazine, capmatinib, givosiran, and peginterferon.

*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.

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Why AdvaCare Pharma?

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