Aminophylline Injection

Always consult a medical doctor or patient care specialist before using aminophylline.

Indications and Usage

Aminophylline works as both a non-selective phosphodiesterase inhibitor and non-selective adenosine receptor antagonist. By acting on these receptors, aminophylline causes bronchodilation, diuresis, cardiac stimulation, and gastric acid secretion.

Contraindications

Aminophylline injection is contraindicated in patients with developed hypersensitivity to ethylenediamine or those allergic to theophylline, caffeine, theobromine, or any of the excipients. Aminophylline is also contraindicated in patients with acute porphyria.

Precautions

Do not take aminophylline if:

• You are allergic to aminophylline or other containing ingredients;
• You are using dipyridamole or halothane concurrently;
• You have asthma, kidney problems, or liver problems;
• You have a history of active peptic ulcers and cardiac arrhythmias;
• You are using a lot of xanthine-containing products.

There is little recorded evidence of use of aminophylline injection during pregnancy or breast feeding, so consult your doctor or healthcare professional before using aminophylline. Theophylline can be excreted into breast milk, but it is unlikely to cause serious adverse reactions.

Tell your doctor if you have heart problems, lung disease, liver disease, kidney disease, stomach ulcers, or an overactive thyroid. The drug may affect lab tests and results, so let your doctor or dentist know you are taking this medication. Watch your blood sugar closely if you have high blood sugar or diabetes.

It is advisable to limit your ingestion of caffeine because this drug may cause nervousness, shakiness, and a faster heartbeat. Consult with your doctor before you drink or smoke while using this medication. Consult with your doctor about any medications you are taking.

Driving or operating machinery is safe while using aminophylline as it does not cause dizziness or induce sleep.

Administration and Dosage

Your physician will prescribe your dose and schedule as this medicine is given through a needle placed in a vein. Do not exceed what they advise. Maximum dose of elderly patients (60 years of age or older) is 400mg/day.

Interactions

Aminophylline can have many possible interactions with other drugs, such as cimetidine, erythromycin, tacrine.

Consult with your doctor about medications you are taking or existing medical conditions you have before your treatment with aminophylline.

Overdose

Symptoms of overdose include trouble breathing and passing out. Other symptoms of overdose may include: generalized seizures and life-threatening cardiac arrhythmias. These symptoms should be reported to a medical professional. If you experience any of these symptoms, seek medical help urgently.

Adverse Reactions

Mildly adverse reactions with low dosages can include nausea, vomiting, headache, and insomnia. Higher dosages of aminophylline may lead to diarrhea, irritability, restlessness, fine skeletal muscle tremors, and transient diuresis.

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