Syphilis is a sexually transmitted bacterial infection caused by the bacterium Treponema pallidum. The disease is highly contagious. However, infected individuals are often unaware of infection. Syphilis occurs in three stages. The primary infection manifests 10-90 days after exposure and causes small painless sores in the genital region or around the mouth. The secondary phase can last up to three months and causes a rosy “copper penny” rash on the palms and feet, groin warts, swollen lymph glands, fever, and weight loss. The final stage of infection can lead to severe problems with the heart, brain, and nervous system, which can lead to paralysis, blindness, dementia, deafness, impotence, and death. Males are more susceptible to syphilis.
Syphilis can be prevented by avoiding intimate contact with infected individuals or using a condom. Although incidences of syphilis have declined dramatically since the development of penicillin in 1940, the disease still has a significant presence in sub-Saharan Africa, and contributes to 20% of prenatal deaths.
With several vaccines currently in development, the disease is projected to decline in the coming years. Prior to the millennium approximately 12 million people were infected with syphilis. Recently, however, the rate of infection has dropped dramatically. If left untreated, the mortality rate of the disease has been shown to be between 8% and 58%, emphasizing the importance of getting checked and treated.
AccuQuik’s syphilis diagnostic test kits are extremely reliable and accurate in 99% of cases. Certain medical factors may influence the result of the test. Individuals taking other medications should consult a doctor before taking the test.
Treatment of syphilis depends on the amount of time that has passed since contraction of the infection. If the individual has been infected for less than one year, then a single dose of penicillin, tetracycline, doxycycline, or another suitable antibiotic should be sufficient to treat the disease. If more than a year has passed, multiple doses may be required for treatment.
- This is newer technology which is rapid, sensitive, and specific;
- This technology is portable, automatic, and easily disposable;
- The sensitivity and specificity is fully validated and currently fulfills the basic requirement of a rapid diagnostic test;
- They are affordable, available, and able to be used as a point of care test.
Bring all the reagents and specimens to room temperature. Open the sealed pouch and remove the test strip from the foil pouch and place on a clean, dry surface.
Identify the test strip for each specimen or control. Apply at least 80 μl of specimen to the sample pad behind the MAX line at the bottom of the test strip.
Wait for the colored bands to appear. Read the results within 10-15 minutes. Do not interpret the results after 20 minutes.
If only one color band appears on the control region, with no apparent band on the test region, the test kit has produced a negative result. If distinct color bands appear on the control and regions test, then the kit has produced a positive result. If there is no visible band at all or only one colored band appears on the test region, the results are invalid. The test should be repeated using a new device.