AdvaCare is a GMP manufacturer of Sulfadoxine Pyrimethamine syrup.
Sulfadoxine pyrimethamine syrup is an antimalarial to treat and prevent malaria when other medicines may not be effective or appropriate. It works by blocking the formation of folinic acid in the malaria organism, killing the parasite.
Sulfadoxine pyrimethamine syrup is a sulfonamide-pyrimethamine antiprotozoal. It may be used alongside other antimalarial medications such as artesunate. Sulfadoxine competes with p-aminobenzoic acid in the biosynthesis of folate and pyrimethamine is a selective inhibitor of protozoal dihydrofolate reductase, which prevents the synthesis of tetrahydrofolate. The synergy between the two leads to a more effective treatment of malaria.
Drink extra fluids while taking the medication. Take the medication after a meal. Do not chew before swallowing.
As with all pharmaceuticals, some unwanted effects can occur from the use of sulfadoxine pyrimethamine syrup. Always consult a doctor or health care professional for medical advice before use.
Common side effects include, but may not be limited to diarrhea, dizziness, headache, vomiting, or nausea. Seek medical attention if the following develop: severe allergic reactions, dark urine, decreased urination, depression, hallucinations, lack of coordination, unusual bruising or bleeding, or tingling/numbness in the skin.
For a comprehensive list of all possible effects, consult your doctor.
If any symptom persists or gets worse, or you notice any other symptom, then please call your doctor immediately.
Always consult your doctor or pharmacist before taking sulfadoxine pyrimethamine syrup.
If your condition does not improve or becomes worse, then call your doctor.
Do not drive or operate machinery until you know how sulfadoxine pyrimethamine syrup affects you.
Do NOT use sulfadoxine pyrimethamine syrup if:
- Allergic to pyrimethamine or sulfadoxine;
- Have severe kidney or liver problems;
- Younger than 2 months.
Do not use sulfadoxine pyrimethamine syrup during pregnancy or breast. Consult your doctor or health care professional before having/taking/using sulfadoxine pyrimethamine syrup.
Refer to your doctor or pharmacist for guidelines on dosage. Do not exceed what they advise. Possible interactions include methotrexate. Consult with your doctor about any medications you are taking, before your treatment with sulfadoxine pyrimethamine syrup.
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