Dexamethasone Tablets

Always consult a medical doctor or patient care specialist before using dexamethasone tablets.

Indications and Usage

Dexamethasone is indicated in the treatment of arthritis, blood/hormone/immune system disorders, allergic reactions, certain skin and eye conditions, breathing problems, certain bowel disorders, and certain cancers. It is also used as a test for an adrenal gland disorder (Cushing’s syndrome).

This medication is a corticosteroid hormone (glucocorticoid). It decreases your body’s natural defensive response and reduces symptoms such as swelling and allergic-type reactions.

Contraindications

Dexamethasone tablets are contraindicated in systemic fungal infections.

Precautions

Do NOT use dexamethasone tablets if you:

• Are allergic to any of the ingredients in dexamethasone tablets.
• Have a history of angioedema associated infections, kidney disease, liver disease, mental/mood conditions, thyroid disease, stomach/intestinal problems, high blood pressure, heart problems, brittle bones (osteoporosis), history of blood clots.;
• Have diabetes mellitus or renal impairment.

Use of dexamethasone tablets during pregnancy or breast feeding is not harmful since there is no scientific research or data available whether they can cause any harm to fetus. Consult your doctor or health care professional about the possible risks before taking dexamethasone tablets.

This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before taking this medication or before breast-feeding.

Driving or operating machinery should be avoided, as it may cause tiredness and drowsiness.

Administration and Dosage

Refer to your doctor or pharmacist for guidelines on dosage. Do not exceed what they advise.

Usual does for adult varies from 0.75 to 9mg per day depending on the disease being treated.

After a successful response, a maintenance dosage should be determined by decreasing the initial drug dosage in small decrements at appropriate time intervals until the lowest dosage that maintains an adequate clinical response is reached.

Interactions

Dexamethasone may interact with the following medications: aminoglutethimide, birth control pills, certain cancer drugs, cholestyramine, digoxin, antiplatelet drugs, NSAIDs such as aspirin/celecoxib/ibuprofen, ephedrine, estrogen hormone replacement, isoniazid, mifepristone, rilpivirine and thalidomide.

Overdose

Symptoms of overdose include trouble breathing and passing out. These symptoms have to be reported to the medical health professional. Seek medical help urgently.

Adverse Reactions

Some of the reported adverse reactions are anaphylactoid reaction, anaphylaxis, angioedema, bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, congestive heart failure, fat embolism, hypertension, hypertrophic cardiomyopathy in premature infants.

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