Promethazine HCl Syrup (box of 1 bottle)
Promethazine HCl Syrup (box of 1 bottle)
*Packaging color may differ according to distribution region.

Promethazine HCL Syrup

Promethazine HCL Syrup is an antihistamine medicine used for allergies and motion sickness. This pharmaceutical syrup is manufactured by AdvaCare Pharma in its ISO/GMP-certified facilities that adhere to all health, safety, and environmental regulations.



What is Promethazine?

Therapeutic Class:

Active Ingredients: Promethazine HCL

Promethazine HCL Syrup is used to treat symptoms caused by allergic rhinitis and allergic conjunctivitis. This medication is also indicated for use as an antiemetic agent in the active and prophylactic treatment of motion sickness. When combined with other drugs, Promethazine may be used to treat anaphylaxis.

Promethazine HCL may also be prescribed as a sedative. It is also used to control nausea or vomiting associated with certain types of anesthesia or surgery.

Promethazine is classified in the family of medicines called phenothiazines. It is an H1-antagonist with anticholinergic, sedative, and antiemetic effects, and some local anesthetic properties. It works by preventing the release of histamine. Histamine is released when the body is exposed to certain allergies, such as pollen, chemicals, mold, dander, and drugs.

AdvaCare Pharma is a producer and exporter of Promethazine HCL Syrup. This medicine is produced in our GMP-certified facilities in China, India, and the USA. These facilities are routinely audited to ensure they comply with health, safety, and environmental standards.

Why choose us as your Promethazine Syrup manufacturer?

AdvaCare Pharma is a reputable and leading manufacturer of Promethazine Syrup, and other pharmaceutical syrups, with a presence in 45 countries. We utilize a unique supplier-distributor relationship that differentiates us from other large-scale medical manufacturers. Promethazine HCL Syrup is a GMP-certified product that is part of AdvaCare range of over 4,000 pharmaceuticals, medical devices, supplements, and veterinary products available for global exportation.


What is Promethazine used for?

It's also used to:

  • relieve allergy symptoms, like rash, itching, and runny nose.
  • treat and prevent symptoms associated with motion sickness.
  • control nausea and vomiting, such as during anesthesia or chemotherapy.
  • treat insomnia or promote sedation.

It may be used as a sedative or anti-anxiety agent before or after surgery or during labor.

Promethazine HCL can be combined with other medications to treat anaphylaxis or as an adjuvant with opiate painkillers.

How is Promethazine HCL Syrup used?

This medication has been manufactured as a liquid to be taken orally. This medication can be taken with or without food.

What dose should be taken?

For the treatment of allergic conditions, the usual dose for adults is 6.25-25mg, taken three times a day (before meals and at bedtime). The maximum dosage is 100mg in a day.

For children over 2 years old, the usual dose is 0.1-0.5mg/kg, taken every 6 hours. The exact dosage and duration are dependent on age, body weight, and severity of infection. The maximum dosage is 12.5 per dose

The exact dosage is based on medical condition, response to the treatment, age, and weight. Refer to a doctor or pharmacist for guidelines on dosage. Do not exceed the advisable dosage.

Side Effects

As with all pharmaceuticals, some unwanted effects can occur from the use of Promethazine HCL Syrup.

Common side effects include, but may not be limited to:

  • dizziness
  • drowsiness
  • confusion
  • constipation
  • blurred or double vision
  • dry mouth
  • sensitivity to the sun

Call a doctor if more serious side effects occur, such as:

  • fainting
  • slow heartbeat
  • mood changes such as hallucinations, irritability, confusion
  • unusual or uncontrolled movements
  • tremors
  • difficulty with urination
  • easy bruising or bleeding
  • signs of an infection such as fever or sore throat
  • severe abdominal pain
  • persistent nausea or vomiting
  • jaundice
  • slow or shallow breathing
  • seizures
  • symptoms of neuroleptic malignant syndrome (high fever, muscle stiffness, changes in mental state, irregular heartbeat)

For a comprehensive list of all side effects, consult a doctor or pharmacist.

If any symptom persists or gets worse, or you notice any other symptoms, please call your doctor immediately.


Do NOT use Promethazine HCL Syrup if:

  • You are allergic to promethazine or other phenothiazines.
  • You are hypersensitive to sulfites.
  • You have liver disease.
  • You have a history of seizures.
  • You have chronic obstructive pulmonary disease.
  • You have sleep apnea or other breathing disorder.
  • You have glaucoma.
  • You have problems with urination.
  • You have an adrenal gland tumor.
  • You have low levels of calcium in the blood.

Drug interactions may increase the risk of serious side effects or change how certain medications work.

Driving or operating machinery should be avoided, as the medication may cause sedation. Alcohol should be avoided, as it may worsen the adverse effects caused by Promethazine HCL.

Do not prescribe to patients under 2 years old, as there have been some reported fatalities due to respiratory depression. Use the lowest effective dose for patients over 2 years old.

*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.

You might be interested in...

Ambroxol HCL Syrup (box of 1 bottle)
Ambroxol Syrup
Dextromethorphan Syrup (box of 1 bottle)
Dextromethorphan Syrup
Desloratadine Syrup (box of 1 bottle)
Desloratadine Syrup
Cold Syrup (box of 1 bottle)
Cold Syrup
Cold&Flu Relief™, Cold&Flu Relief MAX™
Montelukast + Levocetirizine Syrup (box of 1 bottle)
Montelukast + Levocetirizine Syrup
Isoniazid Syrup (box of 1 bottle)
Isoniazid Syrup
Iron Syrup (box of 1 bottle)
Iron + Folic Acid + Ascorbic Acid Syrup
Decongestant Syrup (box of 1 bottle)
Decongestant Syrup
Decongestant (Anti-Cough)™, Decongestant (Anti-Cough) KIDS™

Why AdvaCare Pharma?

As an industry leader, we are aware of our responsibility to provide affordable and sustainable solutions to improve healthcare worldwide.

High Quality Affordable Products
Globally Recognized Brands
Wide Product Range
Regulatory Affairs Expertise
Flexible Production Lines
Marketing & Logistics Support