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Antibiotic
Tylosin Tyrate
Product Information
General Information:
AdvaCare is a GMP manufacturer of Tylosin Tartrate liquid injection.
Tylosin Tartrate Injection has a broad spectrum of activity against gram-positive organisms and a limited range of gram-negative organisms. It is found naturally as a fermentation product of Streptomyces fradiae.
Tylosin tartrate injection treats bacterial infections such as bovine respiratory complex, metritis, and acute mastitis in cattle; mastitis in sheep and goats; enteritis, pneumonia, erysipelas, and infectious arthritis in swine; and soft tissue infections in small animals.
It is important to note that AdvaCare’s tylosin tartrate is for veterinary purposes only, you should only use the kind that has been prescribed by a veterinary doctor or animal care specialist for an animal.
Side Effects:
As with all veterinary medicine, some unwanted effects can occur from the use of tylosin tartrate. Always consult a veterinary physician or animal care specialist for medical advice before use.
The most common negative tylosin tartrate side effects associated include pain and local reactions at intramuscular injection sites, anorexia, and diarrhea. Some negative effects observed specifically in swine include mild anal protrusions with pruritus, erythema, and diarrhea, as well as edema of rectal mucosa.
For a comprehensive list of all possible effects, consult a veterinary physician.
If any symptom persists or gets worse, or you notice any other symptom, then please seek veterinary medical treatment immediately.
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For more information about our Tylosin Tartrate Injection
email us at: info@advacarepharma.com
Additional Information
Always consult a veterinary physician or animal care specialist before using tylosin tartrate injection.
Indications and Usage
Tylosin Tartrate Injection is indicated in the treatment of bovine respiratory complex (shipping fever, pneumonia) usually associated with Pasteurella multocida and Actinomyces pyogenes; foot rot and calf diphtheria caused by Fusobacterium necrophorum and metritis caused by Actinomyces pyogenes in beef cattle and nonlactating dairy cattle.
In swine, tylosin tartrate is indicated in the treatment of swine arthritis caused by Mycoplasma hyosynoviae; swine pneumonia caused by Pasteurella spp.; swine erysipelas caused by Erysipelothrix rhusiopathiae; acute swine dysentery associated with Treponema hyodysenteriae.
Contraindications
Tylosin is contraindicated in animals allergic to other macrolide antibiotics (e.g., erythromycin). Some studies have shown that tylosin is contraindicated in horses, which may result in severe and fatal diarrheas whenever used in these species.
Administration and Dosage
For intramuscular injection only.
Usual dosage is as follows: 8mg of tylosin per 0.45kg body weight in cattle once daily (1 mL of the 200 mg per 25 pounds). Swine – 4mg per 0.45 kg per body weight (1 mL of the 200 mg per 50 pounds). Tylosin injections shouldn’t be administered if any hypersensitivity is discovered.
Treatment should be continued 24 hours or when the patient is asymptomatic. Treatment should not be exceeded more than 5 days. Administration of dosage more than 10 ml in cattle and more 5ml in swine per site is not recommended.
Refer to an animal care specialist for guidelines on dosage. Do not exceed what they advise, and complete the full treatment, as stopping early can result in a recurrence or worsening of the problem.
Precautions
Adverse reactions, including shock and death may result from over dosage in baby pigs. Administration of dosage more than 0.5ml into pigs weighing less than 25 pounds is not advisable.
Warnings
Discontinuation of the therapy in cattle 21 days before slaughter is recommended. In swine, discontinue the therapy 14 days prior to slaughter. Use of therapy in lactating dairy cattle is not recommended.
A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.
Overdose
Tylosin is relatively safe in most overdose situations. Shock and death have been reported in baby pigs overdosed with tylosin.
Interactions
Studies have shown that, tylosin tartrate may increase digoxin blood levels with resultant toxicity. It is recommended for an erythromycin monograph reference for more information on potential interactions.
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