*AdvaCare Metamizole Sodium Tablets are GMP certified.

**AdvaCare Metamizole Sodium Tablets are manufactured in our facilities located in China, India and USA.

(choose the specifications you require below)

Dosage:

500mg

*or according to distributor/market composition

Packaging:

10 tablets/blister, 10 blisters/box;1,000 tablets/bottle

*or according to distributor/market requirements

Therapy:

Analgesic, Anti-pyretic, Antiasthmatic

Active Ingredients:

Metamizole Sodium

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Product Information

General Information:
AdvaCare is a GMP manufacturer of Metamizole Sodium tablets.

Metamizole sodium tablets are a non-opioid analgesic and antipyretic medication which belongs to the class of NAISD’s. It is used primarily for the relief of pain and fever.

It is used to treat pain and fever from headache, toothache, arthralgia, neuralgia, high fever, pain after surgeries, and other illnesses that do not respond to other NAISD’s.

Side Effects:
As with all pharmaceuticals, some unwanted effects can occur from the use of metamizole sodium tablets. Always consult a doctor or health care professional for medical advice before use.

Common side effects include, but may not be limited to diarrhea, nausea, rashes, skin reactions, red coloration of urine, drop in blood pressure, shock, and intolerance. For a comprehensive list of all possible effects, consult your doctor.

If any symptom persists or gets worse, or you notice any other symptom, then please call your doctor immediately.

Additional Information

Always consult a medical doctor or patient care specialist before using metamizole tablets.

Indications and Usage

Metamizole belongs to the class of analgesics. It is indicated in the treatment of severe post-traumatic or post-operative pain.

Metamizole sodium tablets are also used for the treatment of respiratory, gastroenteritic and urogenital diseases, such as asthma and pneumonia. This medication is effective in blood poisoning and pyogenic dermatitis.

The mechanism of action is based on the inhibition of central cyclooxygenase-3 and on the activation of cannabinoid and opiodergic system.

Contraindications

Metamizole is contraindicated in patients with a deficiency of glucose 6 phosphate dehydrogenase, severe hepatic insufficiency, severe renal insufficiency and acute intermittent porphyria.

Precautions

Do NOT use metamizole sodium tablet if you:

  • Have hypersensitivity towards metamizole sodium tablet or any of the excipients in the tablet;
  • Are younger than 18 years of age;
  • You suffer from low blood pressure or hypotension.

Use of metamizole sodium tablet during pregnancy or breast feeding should be avoided. This medication passes into breast milk and can lead to delirious effect in the nursing infant. Consult your doctor before taking this medication or before breast-feeding.

Driving or operating machinery has no affect your ability to drive especially if you are taking it for the first time or if your doctor changes the dose.

Administration and Dosage

Refer to your doctor or pharmacist for guidelines on dosage. Do not exceed what they advise. Usual recommended dose for adults is: 500mg 3-4 times a day. The maximum dosage is 4000mg.

Interactions

Metamizole sodium may interact with drugs such as anticoagulants, antibiotics, sedatives and hypotonics.

Overdose

If someone overdoses might have symptoms nausea, vomiting, seizures, dizziness, coma, mydriasis, liver damage, kidney damage, breathlessness or passing out. This has to be reported to the medical health professional. Seek medical help urgently.

Adverse Reactions

Some of the reported adverse reactions by metamizole sodium may be abdominal discomfort, maculopapular rash, Stevens-Johnson syndrome, Lyell syndrome, agranulocytosis, hypotension, bronchospasm, arrhythmia and other allergic reactions.

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