Calcium Folinate Tablets (box of 100 tablets)
Calcium Folinate Tablets (blister of 10 tablets)
Calcium Folinate Tablets (box of 100 tablets)
Calcium Folinate Tablets (blister of 10 tablets)
*Packaging color may differ according to distribution region.

Calcium Folinate Tablets

Calcium Folinate Tablets are a medicine that reduces the harmful effects of Methotrexate and other anti-cancer drugs. This pharmaceutical drug is manufactured by AdvaCare Pharma, using only high quality ingredients, in its ISO/GMP-approved production plants.



What is Calcium Folinate?

Therapeutic Class:

Active Ingredients: Calcium Folinate

Calcium Folinate, also called folinic acid or leucovorin calcium, is an adjuvant medication used in cancer chemotherapy. It is typically used to reduce the harmful effects of certain types of anticancer medications, such as methotrexate. Calcium Folinate is also used to treat some types of megaloblastic anemia.

Calcium Folinate is a reduced form of folic acid. Calcium Folinate allows nucleic acid synthesis to continue despite the presence of a folic acid antagonist.

AdvaCare Pharma is a GMP-certified manufacturer and exporter of Calcium Folinate Tables. We offer a wide range of high-quality and cost-effective oncology medications that are available for distribution. These medications have been produced in our facilities in China, India, and the USA.

Why are we a trusted Calcium Folinate manufacturer?

AdvaCare Pharma manufactures a variety of oncology medications, including Calcium Folinate Tablets, at GMP-certified facilities. We are committed to producing cost-effective, high-quality cancer treatments that meet the highest industry standards and are readily available to cancer patients worldwide. Our global reach extends to over 65 markets, where we supply our products to distributors, hospitals, pharmacies, NGOs, and government institutions.


What is Calcium Folinate used for?

It's used to reduce the harmful effects (anemia, thrombocytopenia, etc.) of certain types of anticancer medications, like methotrexate or trimethoprim. Calcium Folinate is also used with fluorouracil to treat cancers of the:

  • colon and rectum
  • esophageal
  • gastrointestinal tract
  • head and neck

It is also used to treat a megaloblastic type of anemia.

How are Calcium Folinate Tablets used?

This medication has been manufactured to be taken orally.

What dose should be taken?

When used as an adjuvant to methotrexate, the usual dosage for an adult is 15mg every 6 hours, until methotrexate levels have been lowered.

For megaloblastic anemia, the usual dosage is 1 tablet per day.

Refer to a doctor or pharmacist for guidelines on dosage. Do not exceed what they advise.

Side Effects

As with all pharmaceuticals, some unwanted effects can occur from the use of Calcium Folinate Tablets.

Seek medical attention if the following symptoms (known as anaphylactic reaction) develop:

  • skin itching
  • convulsions
  • difficulty in breathing or swallowing

For a comprehensive list of all possible effects, consult a doctor.

If any symptom persists or gets worse, or you notice any other symptom, please call your doctor immediately.


Do NOT use Calcium Folinate Tablets if:

  • You are allergic to Calcium Folinate or any other ingredients of this medicine.
  • You are trying to treat a type of anemia caused by vitamin B12 deficiency.
  • You take anti-neoplastic folic acid antagonists, such as methotrexate, to reduce or prevent clinical toxicity.

Possible interactions may occur with other pharmaceutical products. Consult with your doctor about any medications you are taking before starting your treatment with Calcium Folinate Tablets.

There is little evidence with regards to the use of Calcium Folinate during pregnancy or breastfeeding, so consult a doctor or healthcare professional before taking this medicine.

Driving or operating machinery is okay, as this medication does not cause any serious ailment.

*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.

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Why AdvaCare Pharma?

As an industry leader, we are aware of our responsibility to provide affordable and sustainable solutions to improve healthcare worldwide.

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