Bromazepam Tablets (box of 100 tablets)
Bromazepam Tablets (blister of 10 tablets)
Bromazepam Tablets (box of 100 tablets)
Bromazepam Tablets (blister of 10 tablets)
*Packaging color may differ according to distribution region.

Bromazepam Tablets

BromaCare™
Bromazepam Tablets are a benzodiazepine drug indicated for anxiety and panic disorders. These tablets are manufactured by AdvaCare Pharma, a globally renowned producer and supplier of quality pharmaceutical drugs, in its ISO and GMP-compliant facilities.

Dosage

Packaging

What is Bromazepam?

Therapeutic Class:

Active Ingredients: Bromazepam

Bromazepam Tablets are an anxiolytic drug used to treat severe anxiety or panic disorders. It is typically prescribed as short-term relief while other treatments take effect. Bromazepam is also prescribed as a sleep aid, as a sedative before minor surgery, or to reduce the effects of alcohol or opiate withdrawal.

Bromazepam is classified as a classical benzodiazepine. It has an intermediate onset; at low doses, this drug displays anxiolytic effects, while higher doses are associated sedative, hypnotic, and skeletal muscle relaxant effects. The active ingredient works by binding to the GABA-A receptor.

Bromazepam Tablets are produced with a dosage of 1.5mg or 3mg. The tablets are packaged in a blister pack and available in boxes of 100 tablets.

AdvaCare Pharma is a manufacturer and supplier of Bromazepam Tablets. This drug is produced in our GMP-certified facilities in China, India, and the USA. Our factories are thoroughly vetted to ensure it meets health, safety, and environmental standards.

Why are we a leading Bromazepam manufacturer?

As a reputable Bromazepam manufacturer, we are dedicated to ensuring that GMP guidelines and standards strictly apply to the manufacture of our entire range of 200+ pharmaceutical treatments in tablet dosage form.

AdvaCare Pharma is an American pharmaceutical company committed to the manufacture of high-quality, affordable pharmaceuticals for a global market. The extensive international network that we partner with includes pharmaceutical distributors, hospitals, pharmacies, and a variety of other medical institutions. Our vision is to manufacture Bromazepam Tablets, and other quality-assured oral solid treatments, that get into the hands of those that need them most.

Uses

What is Bromazepam used for?

It is used to treat acute or severe anxiety and panic disorders. It is also used to induce sleep.

How are Bromazepam Tablets used?

This medication is intended to be taken orally. The tablets should be taken with a full glass of water. Typically, Bromazepam Tablets are taken about 30-60 minutes before mealtime or as indicated by a healthcare professional. Do not crush the tablet.

How should Bromazepam Tablets be stored?

It is recommended to keep this medicine in its original packaging until use. Bromazepam Tablets should be stored in a cool and dry location between 15-30°C. Keep this medicine out of the reach of children and pets. Before use, check the expiry date printed on the packaging and discard any outdated medicines.

What dose should be taken?

Adult Dosing Dosage may vary based on different medical indications:

  • For anxiety (outpatient), the usual dose is 1.5-3mg, taken up to 3 times per day. The starting dose should begin at the lowest possible dose and gradually increased.
  • For severe anxiety (hospitalized), the usual dose is 6-12mg taken 2-3 times per day. The maximum dosage is 60mg per day. Treatment should be as short as possible and should not exceed 8-12 weeks including tapering.
  • For anxiety in geriatric patients, the maximum dosage is 3mg per day, taken in divided doses.

Renal Dosing It may be necessary to consider a dose reduction for patients with renal impairment.

Hepatic Dosing For patients with mild to moderate hepatic impairment, the dose should be kept started at the lower end of the range.

For patients with severe hepatic impairment, this drug is contraindicated.

The dosage is based on medical condition, response to treatment, age, and weight. Refer to a doctor or pharmacist for guidelines on dosage. Do not exceed what they advise.

What happens if a dose is missed?

If a dose has been missed, take it as soon as possible. If it is nearly time for the next dose, skip the missed dose. Never take 2 doses at the same time.

Can Bromazepam Tablets be stopped abruptly?

It is not advised to suddenly stop taking this medication unless a healthcare professional has indicated otherwise.

Stopping this medication may cause withdrawal symptoms. If Bromazepam has been taken for a prolonged period of time, it will need to be tapered under the guidance of a healthcare provider.

What are the symptoms of withdrawal from Bromazepam?

The risk of withdrawal is higher for someone who has been taking this Bromazepam at a high dose or for a long time. When following a tapering schedule, it is possible to prevent or reduce withdrawal and rebound symptoms. Some symptoms of withdrawal include:

  • catatonia
  • delirium tremens
  • confusion
  • depression or mania
  • dissociation
  • hallucinations
  • psychosis
  • suicidal thoughts
  • seizures

Who can use Bromazepam Tablets?

Bromazepam Tablets can be given to adults, but caution is advised for specific groups of patients.

Pregnant Bromazepam should only be used in pregnant women if the benefits outweigh the risks. This medication may cause fetal harm.

Breastfeeding The use of Bromazepam in breastfeeding women is not recommended. It should only be used if the benefits outweigh the risks. This drug is known to pass into milk.

Children This medication is not recommended for children and adolescents under 18. There is insufficient data to assess the safety and efficacy of pediatric patients. When giving Bromazepam to a pediatric patient, the dose must be adjusted according to body weight.

Geriatric This population may have an increased risk of side effects such as drowsiness or impaired coordination. Reduced dosages are recommended for elderly patients.

Are there any monitoring parameters recommended for patients using Bromazepam?

It is recommended to regularly monitor heart rate and blood pressure and periodically monitor CBC, as well as respiratory, liver, and renal function.

Can Bromazepam Tablets be used for the long-term treatment of anxiety?

It is recommended to only take this medication for a short period of time, such as 2-4 weeks. The long-term use of Bromazepam may lead to physical dependence or addiction, and continuous use of this drug should only be done under the guidance of a doctor.

Can Bromazepam Tablets be stopped abruptly?

It is not advised to suddenly stop taking this medication unless a healthcare professional has indicated otherwise. Stopping this medication may cause withdrawal symptoms. If Bromazepam has been taken for a prolonged period of time, it will need to be tapered under the guidance of a healthcare provider.

What are the symptoms of withdrawal?

The risk of withdrawal is higher for someone who has been taking this Bromazepam at a high dose or for a long time. When following a tapering schedule, it is possible to prevent or reduce withdrawal and rebound symptoms. Some symptoms of withdrawal include:

  • catatonia
  • delirium tremens
  • depression or mania
  • dissociation
  • hallucinations
  • psychosis
  • suicidal thoughts
  • seizures

Other warnings

It is advised to use caution when prescribing this medication for patients with depressive disorders, psychosis, psychiatric or personality disorders, history of alcohol/drug abuse, or chronic respiratory disease.

This medication can suppress breathing, which may be worsened by breathing problems, brain damage, or other medications which are also centrally acting depressants.

Special care must be exercised during the concomitant use of Bromazepam with opioids, as this combination may cause extreme sedation, respiratory depression, and coma.

Side Effects

As with all pharmaceuticals, some unwanted effects can occur from the use of Bromazepam Tablets.

Common side effects include, but may not be limited to:

  • dizziness
  • drowsiness
  • blurry vision
  • constipation
  • delayed reactions or clumsiness
  • headache
  • slurred speech
  • dry mouth
  • muscle weakness or spasms

Inform your doctor if any of these side effects are persistent or severe.

Contact your doctor if the following develops:

  • increase in anxiety
  • mental or mood changes (e.g. aggressiveness, agitation, etc.)
  • falls or fractures
  • nightmares or difficulty sleeping
  • symptoms of withdrawal
  • urinary problems

Stop taking this medication and seek medical attention in the event of:

  • seizures
  • signs of an allergic reaction
  • suicidal thoughts

For a comprehensive understanding of all potential side effects, consult a medical professional.

If any symptoms persist or worsen, or you notice any other symptoms, please call your doctor immediately.

Precautions

Do NOT use Bromazepam Tablets if:

  • You are allergic or hypersensitive to any of the ingredients.
  • You are allergic to any other benzodiazepine.
  • You have myasthenia gravis or narrow-angle glaucoma.
  • You have severe breathing problems.
  • You have severe liver disease.
  • You have sleep apnea.

Bromazepam is known to interact with many other drugs, including alcohol, certain antibiotics, antihistamines, antipsychotics, azole antifungals, barbiturates, other benzodiazepines, brimonidine, buprenorphine, buspirone, cimetidine, efavirenz, general anesthetics, muscle relaxants, narcotics, seizure medicines, SSRIs, St John's wort, theophylline, and trazodone. This is not a complete list. Consult with your doctor about any medications, supplements, and herbal products you are taking before your treatment with Bromazepam.

Bromazepam Tablets may not be suitable for people with certain conditions, so it is important to consult with a doctor if you have any health conditions. Additional considerations or special monitoring may be necessary for conditions such as:

  • history of any other mood disorder such as depression
  • history of alcohol or drug abuse
  • kidney or liver disease
  • lung disease
  • personality disorder
  • elderly or debilitated

It is not recommended to use this medication during pregnancy and breastfeeding. Consult a doctor or healthcare professional before treatment.

This medicine is known to cause drowsiness or dizziness. It is recommended to avoid driving or operating machinery until the effects of the medicine are clear.

Do not drink alcohol while undergoing treatment with Bromazepam Tablets. Alcohol may worsen the side effects of this medication.

It may be necessary to have certain lab or medical tests while taking this medicine.

Do not share Bromazepam Tablets with others, even if they are suffering from the same health condition. This medicine is known to cause addiction.

Bromazepam 3mg: Why the most common dose?

Bromazepam 3mg is widely prescribed for its effective anxiolytic properties while minimizing sedation. This dosage helps manage anxiety symptoms efficiently and is well-tolerated by most patients. Other doses, such as Bromazepam 1.5mg, are available for milder cases or initial treatment

References

Bromazepam in generalized anxiety: Randomized, multi-practice comparisons with both chlorprothixene and placebo

This randomized, double-blind group-comparative multicenter trial compared bromazepam with a placebo and with chlorprothixene.

This study included 245 patients with generalized anxiety disorder (DSM-III 1980) who were treated for 2 weeks with two daily doses of bromazepam, 3mg or chlorprothixene, 15mg or placebo. Median reductions in Hamilton's Anxiety rating were 12 (bromazepam), 10.3 (chlorprothixene), and 7.3 (placebo).

The results showed the superiority of bromazepam over placebo (median differences 3.3, 95% confidence limits: 0.3 and 6.1), and also tolerance was rated as “at least good” in 85.6% on bromazepam, in 86% on chlorprothixene and in 87.8% on placebo.

The conclusion of this study is that bromazepam and chlorprothixene are both superior to placebo in generalized anxiety states treated in general practice.

*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.

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