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Always consult a veterinarian or animal care specialist before using penicillin G and benzathine penicillin injection.
Indications and Usage
This product is indicated for the treatment of the following bacterial infections in beef cattle:
- Pbacterial pneumonia (expedition fever complex) (Streptococcus, Actinomyces pyogenes, Staphylococcus aureus);
- Upper respiratory infections such as rhinitis or pharyngitis (Actinomyces pyogenes);
- Blackleg (Clostridium chauvoei).
- Hypersensitivity to penicillin and / or procaine;
- Administration to animals with severe renal impairment;
- Concomitant administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
Administration and Dosage
The usual dose is 2 ml penicillin G and benzathine penicillin procaine per 68 kg body weight in beef cattle (subcutaneously only). Injecting penicillin G procaine and benzathine penicillin should not be administered if hypersensitivity is discovered.
Treatment in beef cattle should be limited to two (2) doses administered by subcutaneous injection only.
Consult an animal care specialist for dosage instructions. Do not go over what they advise and complete the entire treatment, as stopping early can lead to recurrence or a worsening of the problem.
Treatment with the recommended dosage is usually given in a single session using multiple intramuscular sites, as appropriate. An alternative regimen can be used, giving half (1/2) of the total dose on day 1 and half (1/2) on day 3.
Exceeding the recommended doses may result in antibiotic residues beyond the withdrawal period.
Animals that have received penicillin G should be closely monitored for at least half an hour. It is recommended to stop the product whenever an allergic reaction or hypersensitivity is discovered.
As with all antibiotic preparations, the use of this drug can lead to the proliferation of unlikely organisms, including fungi. In such cases, consult a veterinarian.
It is advisable to avoid the administration of penicillin in combination with tetracyclines, as some bacterial drugs may interfere with the bacteriostatic action of tetracyclines.
Beef cattle should not be slaughtered for consumption for 30 days after the last treatment. Treatment in beef cattle should be limited to two (2) doses by subcutaneous injection only. Do not inject intramuscularly.
A waiting time has not been established for this product in pre-rumpled calves. Use in calves for the treatment of meat is not recommended.
An excessive dose of penicillin can lead to neuromuscular hyperirritability, seizures or convulsions. With very high overdoses, a diminished immune response can be observed. However, if an overdose is suspected, consult an emergency doctor.
Tetracycline is a bacteriostatic antibiotic that can antagonize the bactericidal effect of penicillin. The simultaneous use of these drugs should be avoided. Co-administration of penicillin and probenecid increases and prolongs serum penicillin levels and slows the rate of excretion by competitively inhibiting renal tubular secretion of penicillin.
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