Metamizole (Dipyrone) Injection (box of 1 vial)
Metamizole (Dipyrone) Injection (box of 1 vial)
*Packaging color and/or animals may vary according to distribution region.

Metamizole (Dipyrone) Injection

Metamizole Sodium Injection is an analgesic drug for parenteral use. A wide range of veterinary injections are produced by AdvaCare Pharma, a leading manufacturer of quality pharmaceutical and veterinary medicines.



What is Metamizole (Dipyrone)?

Therapeutic Class:
Target Species:

Active Ingredients: Metamizole Sodium

Metamizole (Dipyrone) Injection is an analgesic drug used to relieve severe pain and reduce fever in dogs, horses, and livestock like cows, goats, sheep, and pigs. It is an effective treatment for a high fever caused by infections, such as Eperythrozoon, toxoplasmosis, circovirus, and infectious pleurisy.

Due to its antispasmodic properties, it can also be used to treat gastrointestinal, biliary, or urinary colic.

Metamizole Sodium belongs to the family of medicines called ampyrone sulfonates. It displays strong antipyretic, spasmolytic, and analgesic properties and weak anti-inflammatory action. Metamizole is thought to work by inhibiting central cyclooxygenase-3 and activating the cannabinoid and opioidergic system.

AdvaCare Pharma's Metamizole (Dipyrone) Injections are manufactured in GMP-certified facilities located in China, India, and the USA. We routinely inspect our production facilities to ensure our products meet health, safety, and environmental standards.

Why are we a trusted Metamizole manufacturer?

Metamizole (Dipyrone) Injection is manufactured and globally distributed by AdvaCare Pharma, a leading manufacturer of veterinary injections in the pharmaceutical industry. We have been committed to distributing high-quality, GMP-certified veterinary medications for the global market for the past 20 years. To ensure that our products meet and surpass our distributors' requirements, we carry out routine internal and third-party facility audits.


What is Metamizole (Dipyrone) used for?

It's used to reduce fever and treat moderate to severe pain such as:

  • visceral pain (including colic)
  • pain related to cancer
  • post-surgical pain
  • musculoskeletal pain

What animals can be treated with Metamizole (Dipyrone) Injection?

This drug is recommended for dogs, horses, and livestock like cows, horses, sheep, goats and pigs.

How is a Metamizole (Dipyrone) Injection used?

This medication has been manufactured as a liquid, which is packaged in a vial. It is intended to be administered by IM/IV injection. Metamizole (Dipyrone) Injection is intended for veterinary use only.

How should Metamizole (Dipyrone) Injection be stored?

This medication should be stored in a dark, dry location under 30°C. The vial should be sealed tightly.

What is the withdrawal period for Metamizole (Dipyrone)?

The withdrawal time is 5 days.


How much Metamizole (Dipyrone) Injection should be given to cows or horses?

The usual dose is 20-50mg/kg, given at slow rate IV/IM. For horses only use slow intravenous administration.

Side Effects

As with all pharmaceuticals, some unwanted effects can occur from the use of Metamizole (Dipyrone) Injection.

Adverse effects are not common, but there are rare reports of serious side effects such as:

For a comprehensive list of all possible side effects of this medication, consult a veterinary physician.


Do NOT use Metamizole (Dipyrone) Injection for an animal that:

  • has a known allergy or hypersensitivity to any of the ingredients.
  • has heart, liver, or kidney failure.
  • has an ulcer in the stomach or intestines.

Treatment with this drug should be administered with caution if an animal:

  • is pregnant or lactating.
  • has liver disease, kidney disease or GI problems, like an ulcer.
  • is geriatric or debilitated.
*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.

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