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      *AdvaCare Ceftiofur HCL Injection is GMP certified.

      **AdvaCare Ceftiofur HCL Injection is manufactured in our facilities located in China/India/USA.

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      *or according to the distributor/market composition

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      *or according to distributor/market requirements


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        Product Information

        General Information:
        AdvaCare is a GMP manufacturer of Ceftiofur Hydrochloride injection.

        Ceftiofur HCL injection is a broad spectrum cephalosporin antibiotic which is used for treatment and control of swine bacterial respiratory disease (swine bacterial pneumonia) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Salmonella Choleraesuis and Streptococcus suis. It is also used in the treatment of Bovine respiratory disease (BRD, shipping fever, pneumonia) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni.

        It is recommended in the treatment of acute bovine interdigital necrobacillosis (foot rot, pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus.

        It is also used in the treatment of acute metritis (0 to 14 days post-partum) associated with bacterial organisms susceptible to ceftiofur.

        Side Effects:
        As with all veterinary medicine, some unwanted effects can occur from the use of ceftiofur HCL injection. Always consult a veterinary physician or animal care specialist for medical advice before use.

        No side effects have been detected yet, a transient local reaction may occur at the site of injection. If you notice any serious effects or other effects not mentioned on this package, please inform your veterinary surgeon.

        For a comprehensive list of all possible effects, consult a veterinary physician. If any symptom persists or gets worse, or you notice any other symptom, then please seek veterinary medical treatment immediately.

        Additional Information

        Always consult a veterinary physician or animal care specialist before using ceftiofur hydrochloride injection.

        Indications and Usage

        Horses: for treatment in horses associated with Streptococcus zooepidemicus leading to respiratory infections.

        Swine: for treatment associated with Actinobacillus pleuropneumoniae and Pasteurella multocida causing swine bacterial respiratory disease (swine bacterial pneumonia).

        Lambs: for treatment in lambs associated with Mannheimia haemolytica causing respiratory disease (pneumonia).

        Dogs: for the treatment of canine urinary tract infections.


        Contraindications are found in the usage of ceftiofur hydrochloride injection in animals previously discovered hypersensitive towards the drug. Whenever hypersensitivity is discovered in amidst to the administration of this drug, recommended precautions has to be undertaken under the supervision of a healthcare personnel.

        Administration and Dosage

        Usual dosage is as follows: 1mg of ceftiofur hydrochloride per kg body weight in cattle and 2mg of ceftiofur hydrochloride per kg of bodyweight in horses (subcutaneously & intramuscularly). Ceftiofur hydrochloride injection shouldn’t be administered if any hypersensitivity is discovered.

        • The use of ceftiofur hydrochloride may result in local skin reaction at the site of injection especially in cattle which can be cured within 3-5 days. If no improvement is seen; consideration of differential diagnosis has to be undertaken;
        • In horses if administration of the dosage is given under stress conditions; acute diarrhea is observed, which can be fatal therefore discontinuation of the drug is advisable;
        • Use of the drug during breeding is not recommended;
        • Occasionally reversible thrombocytopenia and anemia have been detected in dogs treated with ceftiofur for long periods;
        • Lengthy therapy (greater than 14 days) should be undertaken only with appropriate assessment.

        Refer to an animal care specialist for guidelines on dosage. Do not exceed what they advise, and complete the full treatment, as stopping early can result in a recurrence or worsening of the problem.


        Slaughtering of lambs and swine is not recommended for at least 24 hours after the treatment. No meat withdrawal period or milk withholding time is required for cattle.

        Administrations of the drug to the horses are not advisable which are to be slaughtered for use in food.

        Ceftiofur hydrochloride injection should not be used as a bulk medication for cattle, swine or any other species. Ceftiofur hydrochloride injection should only be used to treat individual animals under the supervision of a veterinary doctor.


        Not applicable.

        Adverse Reactions

        No adverse conditions have been reported.

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