The #1 Distributor-Rated Effective and Affordable Tick & Flea Prevention

The safety profile of TickZero™ is extensively documented and approved by major global regulatory bodies (such as the FDA and EMA) for use in dogs and puppies 8 weeks of age or older. AdvaCare Pharma ensures all TickZero™ formulations meet stringent safety margins, remaining effective and well-tolerated in breeding, pregnant, and lactating dogs across global territories.

The active ingredient in TickZero™ is clinically proven to provide immediate and persistent killing activity. Clinical data shows that most fleas are eliminated within 8 hours, while tick activity is suppressed within approximately 12 hours. This rapid onset makes it a highly effective, fast-acting treatment that maintains persistent protection for up to 12 weeks, providing veterinarians with a reliable solution for immediate and long-term parasite control.

TickZero™ provides a significant clinical advantage for active canines because its efficacy is entirely independent of water exposure. Unlike topical treatments (collars, shampoos, or spot-ons) that can be washed away or require strict "no-water" periods after application, TickZero’s systemic oral delivery ensures the active ingredient remains at therapeutic levels for the full 12-week cycle. This "bath-proof" protection ensures consistent compliance and reliable results regardless of bathing, swimming, or grooming schedules.

Every batch of TickZero is manufactured in facilities that adhere to strict GMP (Good Manufacturing Practice) certification. Our high-quality production process ensures that each chewable tablet contains a precise concentration of its active ingredient, guaranteeing that B2B partners receive a product that is both stable and shelf-ready for international distribution.

TickZero™ provides a broad-spectrum solution by targeting adult fleas (Ctenocephalides canis) and major tick species, including Ixodes ricinus, Dermacentor reticulatus, and Rhipicephalus sanguineus. By significantly reducing infestations of Dermacentor reticulatus, TickZero helps lower the clinical risk of Babesia canis infection. Furthermore, the formulation is effective in the treatment of demodicosis (Demodex canis) and sarcoptic mange (Sarcoptes scabiei var. canis), reinforcing its status as a comprehensive 3-month antiparasitic treatment..