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Always consult your doctor or pharmacist before taking benzyl penicillin sodium powder for injections.
Indications and Usage
Benzyl penicillin sodium powder for injections is indicated for the treatment in several infections caused by susceptible gram-positive aerobic organisms, such as Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Aminoglycosides may be added for synergy against group B streptococcus (S. agalactiae), S. viridans, and Enterococcus faecalis.
Benzyl penicillin sodium may also be used as first or second line agents against susceptible gram-positive aerobic bacilli such as Bacillus anthracis, Corynebacterium diphtheriae, and Erysipelothrix rhusiopathiae.
Do not take benzyl penicillin sodium powder for injections if:
- You are hypersensitive to any of the ingredients;
- You have hypersensitivity towards penicillin ;
- You are diabetic or have kidney problems;
- You have a medical history of heart problems.
Studies have shown that administration of benzyl penicillin sodium powder for injections in pregnancy or in women of childbearing age is safe and does not lead to direct or indirect harmful effects to the unborn baby Although it is not known if benzyl penicillin sodium may be excreted into the breast milk of nursing mothers, it is actively transported from the blood to milk in animals and trace amounts of other penicillin in human milk have been detected.
Consult your doctor or health care professional before taking benzyl penicillin sodium powder for injections.
Substantially high doses of benzyl penicillin sodium can sometimes lead to hypokalaemia (low concentration of blood in the potassium) and hypernatraemia (high concentration of sodium in blood). To prevent from these conditions, a diuretic is always recommended. Electrolyte balance, blood count, and renal function should be monitored if the undergoing high-dosage treatment is for more than 5 days.
In diabetic patients due to high blood glucose levels, delayed intramuscular absorption may be seen.
Overgrowth of non-susceptible organisms or yeast may result from prolonged use benzyl penicillin which has to be carefully monitored in patients for other bigger infections.
Administration and Dosage
Administration of dosage can be given intravenously and intramuscularly.
Refer to your doctor or pharmacist for guidelines on dosage. Do not exceed the recommended dosage. Recommendations of dosage are based on the severity of the infections, age, gender and bodyweight.
Intravenous injection or infusion is recommended whenever there is a requirement of high dosage. To avoid irritation of the central nervous system or electrolyte imbalance, slow delivery of injection should be given; taking at least one minute for each 300 mg (0.5 mega units). Hypernatremia and hypokalaemia are seen when injected with high doses unless the sodium content is taken into account.
Benzyl penicillin sodium powder for injections interacts with other drugs such as: oral contraceptives, probenecid, methotrexate, allopurinol or sulfipyrazone, neomycin and anti-coagulants.
Consult with your doctor about any medications you are taking, before your treatment with benzyl penicillin sodium for injections.
Symptoms of overdose include trouble breathing and passing out. These symptoms have to be reported to the medical health professional and seek a medical help urgently. Excessive levels of benzyl penicillin sodium can be corrected by hemodialysis.
No adverse reactions have been reported.