Albendazole Oral Suspension
Dosage
Packaging
What is Albendazole Oral Suspension 400mg/10ml?
Active Ingredients: Albendazole
Albendazole Oral Suspension is a benzimidazole anthelmintic formulated for human use at a strength of 400mg/10ml (4%). Albendazole is used in the treatment of susceptible helminth infections. Approved indications may vary by country and should follow locally approved prescribing information.
After oral administration, albendazole is converted to its active metabolite, albendazole sulfoxide. It acts by binding to β-tubulin and disrupting microtubule formation in susceptible parasites. This interferes with glucose uptake and energy metabolism, ultimately impairing parasite survival.
The appropriate dose and duration of treatment depend on the type of infection, patient-specific factors and approved local treatment guidelines. Albendazole should be used under the direction of a qualified healthcare professional, and some systemic helminth infections may require specialist supervision and clinical monitoring.
AdvaCare Pharma manufactures Albendazole Oral Suspension in GMP-compliant facilities located in China, India and the United States. The 400mg/10ml human formulation is produced for international pharmaceutical markets, with regulatory and product documentation available to support distributors and registration requirements.
This page covers AdvaCare Pharma's Albendazole Oral Suspension for human use. A separate Veterinary Albendazole Oral Suspension is available for animal health applications.
Why are we a quality Albendazole manufacturer?
AdvaCare Pharma manufactures AlbenCare™ Albendazole Oral Suspension 400mg/10ml for human pharmaceutical markets. The product is supplied as a 4% oral suspension in a 15ml bottle/box. Manufacturing is carried out in GMP-compliant facilities, with quality documentation and registration support available for pharmaceutical distributors and importers according to market requirements.
The human-use formulation is managed separately from AdvaCare Pharma's veterinary albendazole range, with specifications, packaging and regulatory requirements appropriate to its intended market.
Uses
What is Albendazole Oral Suspension used for in humans?
It is used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites.
How is Albendazole Oral Suspension used?
This medication is manufactured as a liquid to be taken orally. It should be taken by mouth with meals, usually 1 to 2 times daily, or as directed by a doctor. Keep out of the reach of children and store at room temperature between 20-25°C.
What determines the dose of Albendazole Oral Suspension?
For treating neurocysticercosis, the usual dose is as follows:
- adults, less than 60kg: 15mg/kg per day, divided and taken with meals. The maximum dose is 800mg per day.
- adults, 60kg or more: 400mg, taken twice a day with food.
- children, over 1 year old: 15mg/kg per day, divided and taken with meals.
For treating hydatid disease, the usual dose is as follows:
- adults, less than 60kg: 15mg/kg per day, divided and taken with meals. The maximum dose is 800mg per day.
- adults, 60kg or more: 400mg, taken twice a day with food.
- children, over 1 year old: 15mg/kg per day, divided and taken with meals for 4 weeks.
Refer to a doctor or pharmacist for guidelines on the exact dosage. The dosage is based on medical condition, response to the treatment, age, and weight.
Can Albendazole Oral Suspension be taken with other medications?
Albendazole Oral Suspension can interact with other medications. Inform the doctor about all the medications and supplements being taken concurrently. The healthcare provider will assess potential drug interactions and adjust the treatment plan as needed to ensure safety and effectiveness against parasitic infections.
How fast does Albendazole work?
It depends on the infection being treated. In some cases, users may begin feeling the effects within a few days, while for others it may take longer. The drug works by disrupting the metabolism of parasitic worms, which can lead to their death or inhibition of growth.
Is Albendazole Oral Suspension effective against all types of parasites?
This drug is effective against a broad range of parasitic worms, including roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and others. Its effectiveness can vary depending on the specific type of parasite and the stage of its lifecycle. It may not be effective against all types, and a combination of antiparasitic drugs may be required.
Can Albendazole Oral Suspension be used in preventive deworming programs?
Albendazole is used in organized preventive chemotherapy or deworming programs in some populations and regions where soil-transmitted helminth infections are endemic. These programs are implemented according to public-health recommendations and local treatment protocols. Individual preventive use should be based on professional medical or public-health guidance rather than self-treatment.
Is Albendazole Oral Suspension safe for pregnant or breastfeeding women?
Albendazole use during pregnancy or breastfeeding should be assessed by a healthcare professional according to the treatment indication and locally approved prescribing information. Albendazole may cause fetal harm based on animal data, so pregnancy requires particular consideration. Available prescribing information reports low concentrations of albendazole and its active metabolite in human breast milk and no reported adverse effects on breastfed infants, although available data remain limited.
Can Albendazole Oral Suspension be used in the elderly?
Clinical data in patients aged 65 years and older are limited. Treatment decisions should therefore consider the individual's medical condition, concomitant medicines and the locally approved prescribing information.
Can Albendazole Oral Suspension be used for animals?
No. The 400mg/10ml AlbenCare™ formulation described on this page is intended for human pharmaceutical use. AdvaCare Pharma manufactures a separate Veterinary Albendazole Oral Suspension with veterinary strengths, packaging, target-species information and administration guidance. View the veterinary Albendazole Oral Suspension here.
Can Albendazole Oral Suspension be taken with alcohol?
Alcohol must be avoided while on this medication. Alcohol can increase the risk of liver problems, which can be further exacerbated by Albendazole, as it is metabolized in the liver.
How should Albendazole Oral Suspension be stored?
Albendazole Oral Suspension should be stored at room temperature, between 20 to 25°C (68 to 77°F). It should be kept in its original container, tightly closed, and out of reach of children. The medication should be protected from light and moisture, and should not be stored in the bathroom or near a sink. Dispose of any unused or expired medication according to local regulations.
Side Effects
As with all medicines, Albendazole Oral Suspension may cause side effects, although not everyone experiences them. The type and frequency of adverse reactions can vary according to the condition being treated, dose and duration of treatment.
Reported side effects of albendazole include:
- headache
- dizziness or vertigo
- nausea or vomiting
- abdominal pain
- reversible hair loss
- elevated liver enzymes
- fever
Seek medical attention promptly if signs of a potentially serious reaction develop, such as:
- unusual bleeding or bruising
- persistent fever, sore throat or other signs of infection
- unusual weakness, tiredness or pale skin
- signs of liver problems, such as yellowing of the skin or eyes or dark urine
- signs of a hypersensitivity reaction, such as rash, hives or swelling
Albendazole has been associated with less common but potentially serious effects involving the liver and blood-cell production. Patients receiving prolonged courses of treatment may require periodic monitoring of blood counts and liver function according to locally approved prescribing information.
This is not a complete list of possible side effects. Patients should consult a healthcare professional and refer to the locally approved product information for comprehensive safety information.
Precautions
Do NOT use Albendazole Oral Suspension if:
- You are allergic to albendazole, benzimidazoles, or any of the ingredients in the Oral Suspension.
- You are pregnant.
Albendazole may not be suitable for people with certain conditions, so it is important to consult with a doctor if:
- You have liver disease, biliary Tract problems (such as a blockage), and blood/bone marrow disorders.
- You could be pregnant or are planning to become pregnant.
Possible interactions may occur with other pharmaceutical products. It may interact with anticonvulsant medications like phenytoin, carbamazepine, and phenobarbital, potentially reducing its effectiveness. It may also interact with antiretroviral drugs such as ritonavir, which may increase the levels of Albendazole in the blood, leading to an increased risk of ill effects.
Consult with a doctor or pharmacist about any medications you are taking before starting your treatment.
Grapefruit products should be avoided during treatment because they can interfere with the metabolism of the medication. This interference can lead to increased levels of albendazole in the bloodstream, potentially enhancing the risk of side effects or adverse reactions.
References
Preventive Chemotherapy to Control Soil-Transmitted Helminth Infections in At-Risk Population Groups
This World Health Organization (WHO) guideline provides evidence-informed recommendations on the use of anthelmintic medicines as part of preventive chemotherapy programs in areas where soil-transmitted helminth infections are endemic.
The guideline discusses the use of albendazole and other anthelmintic medicines in organized public-health deworming programs for defined at-risk populations. Recommendations vary according to factors such as age, pregnancy status, local prevalence of infection, and the population being treated.
The guideline confirms that albendazole can have a role in preventive deworming programs when administered according to established public-health recommendations. Individual treatment or preventive use should follow local medical guidance and approved treatment protocols.
Efficacy and Safety of Albendazole in Hookworm-Infected Preschool-Aged Children, School-Aged Children, and Adults in Côte d'Ivoire: A Phase 2 Randomized, Controlled Dose-Finding Trial
This randomized, controlled dose-finding trial evaluated the efficacy and safety of different doses of albendazole for the treatment of hookworm infection in preschool-aged children, school-aged children, and adults in Côte d'Ivoire.
The study enrolled 38 preschool-aged children, 133 school-aged children, and 196 adults. Participants received different albendazole doses according to their study group, and treatment efficacy was assessed using cure rates and reductions in hookworm egg counts after treatment.
The results demonstrated a dose-response relationship for albendazole against hookworm infection in the studied populations. The findings provide clinical evidence supporting the anthelmintic activity of albendazole, while the appropriate dose and treatment regimen should be determined according to the indication, patient characteristics, and approved local prescribing information.
