Irinotecan HCL Injection (box of 1 vial)
Irinotecan HCL Injection (box of 1 vial)
*Packaging color may differ according to distribution region.

Irinotecan HCL Injection

Irinotecan HCL Injection is an antineoplastic medicine indicated for metastatic cancer of the colon or rectum. This anti-cancer drug is manufactured by AdvaCare Pharma in ISO/GMP-certified facilities with the strictest quality control and safety measures implemented.



What is Irinotecan HCL ?

Therapeutic Class:

Active Ingredients: Irinotecan HCL

Irinotecan Injection is an anticancer drug used for the chemotherapy treatment of metastatic cancer of the colon or rectum. It is a first-line therapy used in combination with fluorouracil and leucovorin. Irinotecan can be used for patients whose disease has progressed or recurred after standard treatment.

The active ingredient, Irinotecan, is a plant alkaloid and a topoisomerase I inhibitor. The active ingredient works by stopping the growth of cancer cells.

AdvaCare Pharma is a trusted global exporter of Irinotecan HCL for Injection. This medication is manufactured in our GMP-certified facilities in China, India, and the USA. Our production facilities are regularly inspected to ensure they comply with WHO's standards, rules, and regulations.

Why choose us as your Irinotecan HCL manufacturer?

AdvaCare Pharma manufactures a variety of oncology medications, including Irinotecan HCL Injection, at GMP-certified facilities. We are committed to producing cost-effective, high-quality cancer treatments that meet the highest industry standards and are readily available to cancer patients worldwide. Our global reach extends to over 65 markets, where we supply our products to distributors, hospitals, pharmacies, NGOs, and government institutions.


What is Irinotecan used for?

It's used to treat cancer. It is a first-line chemotherapy option for metastatic cancer of the colon or rectum. This drug can also be used for patients whose cancer has progressed or recurred after the standard treatment with fluorouracil.

How should Irinotecan Injection be used?

This medication has been manufactured as a liquid solution, which is to be given by injection into a vein. It should only be administered by a doctor or healthcare provider.

What dose should be given?

As monotherapy for colorectal cancer, the usual regimen is 125/m² given by infusion over 90 minutes. It is administered on days 1, 8, 15, 22 followed by 2 weeks no treatment. The cycle should then be repeated.

The usual dose for adults and children is dependent on the type of cancer, its cycle, and other general factors. Refer to a doctor or pharmacist for guidelines on dosage. Do not exceed what they advise.

Side Effects

As with all pharmaceuticals, some unwanted effects can occur from the use of Irinotecan Injection.

Common side effects include, but may not be limited to:

  • nausea
  • vomiting
  • loss of appetite
  • constipation
  • hair loss
  • weakness
  • back pain

Seek medical attention if the following develop:

  • chest pain
  • rash
  • hives
  • itching
  • unusual weight gain
  • difficulty breathing or swallowing

For a comprehensive list of all possible effects, consult a doctor.

If any symptom persists or gets worse, or you notice any other symptoms, please call your doctor immediately.


Do NOT use Irinotecan Injection if: • You show any allergy to one of the components of Irinotecan HCL Injection.

The use of Irinotecan during pregnancy or breastfeeding is not recommended because it can harm the fetus or baby. Consult a doctor or healthcare professional before taking Irinotecan.

Consult with your doctor about any medications you are taking before your treatment with Irinotecan HCL Injection.

Driving or operating machinery should be avoided, as the medication may cause pain, most likely located in the back.

*Regulatory compliance may vary according to production standard, import requirements and/or manufacturing origin.

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