Mesna Injection

Active Ingredients: Mesna

Mesna Injection is a cytoprotective drug used in cancer chemotherapy. It helps protect the bladder and kidneys from hemorrhagic cystitis, a serious side effect of certain anticancer drugs like ifosfamide. Mesna does not change the effect of these antineoplastics, but it does make them less harmful to the body.

Mesna is a sulfhydryl compound that works to detoxify acrolein, a urotoxic byproduct, that accumulates in the bladder.

AdvaCare Pharma is a global distributor and manufacturer of Mesna Injection. This drug is produced in our GMP-certified facilities in China, India, and the USA.

AdvaCare Pharma manufactures a variety of oncology medications, including Mesna Injection, at GMP-certified facilities. We are committed to producing cost-effective, high-quality cancer treatments that meet the highest industry standards and are readily available to cancer patients worldwide. Our global reach extends to over 65 markets, where we supply our products to distributors, hospitals, pharmacies, NGOs, and government institutions.

What is Mesna used for?

It is used to protect the bladder and kidneys during cancer chemotherapy treatments that use cyclophosphamide or ifosfamide.

How should Mesna Injections be used?

This medication has been manufactured as a liquid, which is to be given by injection into a vein. It should only be administered by a doctor or healthcare provider. It is given together with cytotoxic drugs that produce urotoxic byproducts.

What dosage should be given?

For the prevention of Hemorrhagic Cystitis, the usual dose is 240mg/m² for 1.2 g/m² of ifosfamide, given 15 minutes before and 4 and 8 hours after treatment with ifosfamide.

The exact dose for adults and children is based on body size and the dose of ifosfamide. Refer to a doctor or pharmacist for guidelines on dosage. Do not exceed what they advise.

As with all pharmaceuticals, some unwanted effects can occur from the use of Mesna.

For a comprehensive list of all possible effects, consult a doctor.

If any symptom persists or gets worse, or you notice any other symptoms, please call your doctor immediately.

Do NOT use Mesna Injection if: • You are allergic to any component related to Mesna.

Drug interactions may increase your risk for serious side effects or change how your medications work.

Consult with your doctor about any medications you are taking before your treatment with Mesna.

There is little evidence with regards to the use of Mesna during pregnancy or breastfeeding, so consult a doctor or healthcare professional before treatment.