*AdvaCare Antodine Liquid Injection is GMP certified.

**AdvaCare Antodine Liquid Injection is manufactured in our facilities located in China, India and USA.

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10ml vial/box;30ml vial/box;50ml vial/box;100ml vial/box

*or according to distributor/market requirements


Analgesic, Antipyretic, Antibiotic

Active Ingredients:


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Product Information

General Information:
AdvaCare is a GMP manufacturer of Antondine liquid injections.

An Antondine Injection is an analgesic injection with antipyretic. It is a competitive histamine H2-receptor antagonist. The pharmacodynamic effect of antodine is the inhibition of gastric secretion.

Antodine is used in dogs and cats to treat or prevent ulcers of the gastrointestinal (GI) tract, and esophagus. Possible causes of GI ulceration include renal failure, drugs, and stress. The primary value of the H2 receptor antagonists is in treating existing ulcers and erosions. They can be helpful in preventing some types of ulcers, but they are less effective for preventing ulcers due to NSAIDs or corticosteroids.

Antodine is used in horses to treat and prevent the recurrence of gastric ulcers. Though omeprazole has been the more commonly used drug for equine gastric ulcer disease (EGUD), but some clinicians feel that there is also a role for the histamine H2 receptor antagonists.

It is important to note that AdvaCare’s antondine liquid injection is for veterinary purposes only and you should only use the kind that has been prescribed by a veterinary doctor or animal care specialist for an animal.

Side Effects:
As with all veterinary medicine some unwanted effects can occur from the use of antodine liquid injection. Always consult a veterinary physician or animal care specialist for medical advice before use.

Side Effects may include:

  • Famotidine and other H2 receptor antagonists are considered very safe drugs with few side effects. They should be used with caution or at a reduced dose in geriatrics or animals with decreased liver or kidney function.
  • Dogs and cats: Rare: mild diarrhea, nausea, vomiting, and mental confusion, especially in older patients. Very rare: agranulocytosis (decreased white blood cell count). Rapid intravenous administration has been associated with vomiting and transient cardiac arrhythmia.
  • Horses: no specific information regarding side effects in horses was found. Famotidine has been used in horses for more than 20 years and is generally thought to be a very safe drug.
  • Injection site reactions may occur with intramuscular injections.

For a comprehensive list of all possible effects, consult a veterinary physician.

If any symptom persists or gets worse, or you notice any other symptom, then please seek veterinary medical treatment immediately.

Additional Information

Always consult a veterinary physician or animal care specialist before using antodine liquid injections.

If the condition does not improve or becomes worse, then call a veterinary physician or animal care specialist.

Refer to an animal care specialist for guidelines on dosage. Do not exceed what they advise, and complete the full treatment, as stopping early can result in a recurrence or a worsening of the problem.

Usual dosage is as follows:

Intramuscular or intravenous:

Horse: 20 to 50ml.
Cattle: 10 to 33.3ml.
Pig: 5 to 10ml.
Goat: 3.33 to 10ml.
Sheep: 3.33 to 6.66ml.
Dog: 1 to 2ml.

Consult with an animal care specialist about any other medications that are being taken by the animal, and their medical history, before their treatment with antodine liquid injections.

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