Always consult a medical doctor or patient care specialist before using glimepiride tablets.
Indications and Usage
Glimepiride belongs to a class of drugs called sulfonylureas. It is an anti-diabetic drug which works on the pancreas (site of action) to help release insulin. Insulin is a chemical that your body makes to move sugar (glucose) from your bloodstream into your cells. Once the sugar enters your cells, they can use it as fuel for your body.
With type 2 diabetes, your body doesn’t make enough insulin, or it can’t properly use the insulin that it makes, so the sugar stays in your bloodstream. This causes high blood sugar levels (hyperglycemia). Therefore, glimepiride is used to trigger the pancreatic cells (β-cells of islets of langerhans) which eventually help in releasing insulin from those cells and work in lowering the blood glucose levels.
Glimepiride tablets are contraindicated with people suffering from hypoglycemia and diabetes ketoacidosis.
Do NOT use glimepiride tablet if you:
- Are allergic to sulfonylureas or glimepiride tablets;
- Have frequent hypoglycemic episodes;
- Have severe kidney or liver problems;
- Have diabetic ketoacidosis.
Little information is available on the use of glimepiride during pregnancy or breastfeeding. Consult your doctor or health care professional before taking glimiperide.
Administration and Dosage
Refer to your doctor or pharmacist for guidelines on dosage. Do not exceed what they advise. Dosages depend on the diabetes type. The recommended starting dose is 1 to 2mg taken once per day 30-45 minutes before breakfast or the first main meal of the day. The maximum recommended dose is 8 mg taken once per day.
Some products that may interact with this drug include: examples of drugs interacting with glimepiride include quinolone antibiotics, blood pressure and heart medicines, antifungals, and eye infection medications, medications for high cholesterol and triglycerides, depression medicines.
If someone overdoses might have symptoms of hypoglycemia, shaking, excessive sweating, breathlessness or passing out. This has to be reported to the medical health professional and seek a medical help urgently
Some of the reported adverse reactions are abdominal pain, dizziness, hypoglycemia, nausea, sweating, tremors, shaking anxiety, vomiting, confusion, and hypertension. Consult with your doctor about any medications you are taking, before your treatment with glimepiride tablets.