*AdvaCare Metamizole Sodium Injections are GMP certified.

**AdvaCare Metamizole Sodium Injections are manufactured in our facilities located in China, India and USA.

(choose the specifications you require below)

Dosage:

250mg/1ml;500mg/2ml;1g/2ml;2.5g/5ml

*or according to distributor/market composition

Packaging:

10 ampoules/box;100 ampoules/box

*or according to distributor/market requirements

Therapy:

Analgesic, Anti-pyretic, Antiasthmatic

Active Ingredients:

Metamizole Sodium

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Product Information

General Information:
AdvaCare is a GMP manufacturer of Metamizole Sodium Injections

Metamizole is a drug that belongs to the group of analgesics. It is used to treat severe post-traumatic or post-operative pain when treatment with other non-opioid medicines have had no effect. Metamizole sodium injections are used as an analgesic and anti-pyretic to relieve pain and fever.

The mechanism of action is based on the inhibition of central cyclooxygenase-3 and on the activation of the cannabinoid and opiodergic system.

Side Effects:
As with all pharmaceuticals, some unwanted effects can occur from the use of metamizole sodium injection. Always consult a doctor or healthcare professional for medical advice before use.

Common side effects include diarrhea, nausea, rashes, skin reactions, red coloration of urine, drop in blood pressure, shock, and intolerance.

For a comprehensive list of all possible effects, consult your doctor. If any symptom persists or gets worse, or you notice any other symptom not listed, then please call your doctor immediately.

  • For more information about our Metamizole Sodium Injections
    email us at: [email protected]

Additional Information

Always consult a medical doctor or patient care specialist before using metamizole sodium injections.

Indications and Usage

Metamizole sodium injections are used primarily to relieve pain and fever. This medication is also used for the treatment of respiratory, gastroenteritis, and urogenital diseases, such as asthma and pneumonia. It is effective against blood poisoning and pyogenic dermatitis.

Contraindications

Metamizole sodium is contraindicated in some conditions such as:

  • Deficiency of glucose-6-phosphate dehydrogenase;
  • Severe hepatic insufficiency;
  • Renal insufficiency and acute intermittent porphyria.
Precautions

Do not take metamizole sodium if:

  • You are allergic to any of the ingredients;
  • You have low blood pressure;
  • You have glaucoma;
  • You are younger than 18 years.

Metamizole should not be used by pregnant women and nursing mothers. It passes into breast milk and may harm your baby.

Administration and Dosage

Refer to your doctor or pharmacist for guidelines on dosage. Do not exceed what they advise. In acute cases, best results are obtained through slow intravenous injection (1ml per minute) with the patient in recumbent position. It may also be administered intramuscularly.

The usual dose for adults is 5ml intramuscularly or slowly intravenously, and this dose may be repeated every two to three hours. In milder cases, dosage ranges from 2 to 5ml intramuscularly. This medicine is not recommended for children under 3 years of age.

Interactions

Metamizole injections can have many possible interactions with other drugs, such as anti-coagulants, antibiotics, corticosteroids, and anti-diabetic drugs. They may also lead to some adverse effects by some sedatives and hypnotics.

Consult with your doctor about medications you are taking or existing medical conditions you have before you begin treatment with metamizole.

Overdose

Symptoms of overdose include trouble breathing and passing out. Some other symptoms include nausea, vomiting, seizures, dizziness, coma, mydriasis, liver damage, and kidney damage. These symptoms should be reported to a medical professional. If you experience any of these symptoms, seek medical help urgently.

Adverse Reactions

Metamizole sodium might cause some adverse reactions such as abdominal discomfort, maculopapular rash, Stevens-Johnson syndrome, Lyell syndrome, agranulocytosis, low blood pressure, broncospasm, arrhythmia, and allergic reactions. Consult with your doctor about any medications you are taking and any health conditions you have before your treatment with metamizole sodium.

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